Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 9/20 | 0.35 |
| ▸ | RAB9A | P51151 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22877096 | 0.82 | ALDH1A1 (0.35) | KMT2AMEN1TDP1ALDH1A1NPC1 | |
| SCHEMBL11574435 | 0.75 | MEN1 (0.55) | KMT2AMEN1LMNATDP1THRB | |
| SCHEMBL6087828 | 0.75 | LMNA (0.50) | KMT2AMEN1LMNATDP1THRB | |
| SCHEMBL16067426 | 0.74 | MAPT (0.47) | KMT2AMEN1LMNATDP1ALDH1A1 | |
| SCHEMBL22877134 | 0.71 | KDM4E (0.45) | KMT2AMEN1LMNAALDH1A1NPC1 | |
| SCHEMBL4333864 | 0.69 | LMNA (0.60) | KMT2AMEN1LMNATDP1THRB | |
| SCHEMBL16067428 | 0.68 | KEAP1 (0.41) | KMT2AMEN1LMNATDP1CYP2C9 | |
| SCHEMBL11494515 | 0.67 | GAA (0.61) | KMT2AMEN1LMNATDP1ALDH1A1 | |
| SCHEMBL11371969 | 0.66 | LMNA (0.55) | KMT2AMEN1LMNATDP1THRB | |
| SCHEMBL7033768 | 0.66 | LMNA (0.55) | KMT2AMEN1LMNATDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107898-B1 | 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-01-06 | — | — | EP | disclosed |