Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17927648 | 0.83 | PDE2A (0.44) | PDE2ACYP3A4ADRA2AADRA2BADRA2C | |
| SCHEMBL20993296 | 0.79 | PDE2A (0.39) | PDE2ACES2CES1CYP3A4SLC6A2 | |
| SCHEMBL13270913 | 0.78 | ADRB2 (0.54) | PDE2ACYP3A4SLC6A2CYP2D6SLC6A4 | |
| SCHEMBL15119935 | 0.78 | CYP3A4 (0.41) | PDE2ACES2CES1CYP3A4SLC6A2 | |
| SCHEMBL7145782 | 0.77 | ADRA2C (0.57) | PDE2ACES2CES1CYP3A4SLC6A2 | |
| SCHEMBL5225559 | 0.77 | ADRA2C (0.57) | PDE2ACES2CES1CYP3A4SLC6A2 | |
| SCHEMBL12303658 | 0.77 | CES2 (0.49) | PDE2ACES2CES1CYP3A4SLC6A2 | |
| SCHEMBL14539581 | 0.76 | CES2 (0.47) | PDE2ACES2CES1CYP3A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL5354434 | 0.76 | KDM4E (0.58) | PDE2ACES2CES1CYP3A4SLC6A2 | |
| SCHEMBL10306200 | 0.76 | CES2 (0.47) | PDE2ACES2CES1CYP3A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210008045-A1 | PANICINOTAM DERIVATIVE, PREPARATION METHOD AND USE THEREOF | OCEAN UNIVERSITY OF CHINA (CN) | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210008045-A1 | PANICINOTAM DERIVATIVE, PREPARATION METHOD AND USE THEREOF | TPMT, PBRM1, PGM2 | PDE2A 1719/4885CES2 1777/4885CES1 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.