SCHEMBL22879871

SCHEMBL22879871

c1ccc(-c2nc(-c3cccc4cc5sc6ccccc6c5cc34)nc3ccc4ccccc4c23)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.37
MAPT P10636 9/20 0.37
KDM4E B2RXH2 7/20 0.37
HPGD P15428 5/20 0.37
SMN1; SMN2 Q16637 4/20 0.35
RAB9A P51151 4/20 0.35
LMNA P02545 4/20 0.35
NPC1 O15118 3/20 0.35
RECQL P46063 1/20 0.35
HTT P42858 2/20 0.34
NPY1R P25929 1/20 0.34
NPY2R P49146 1/20 0.34
NQO1 P15559 1/20 0.33
NQO2 P16083 1/20 0.33
F9 P00740 1/20 0.32
PTGES O14684 1/20 0.32
ATM Q13315 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
TDP1 Q9NUW8 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22880206 0.96 ALDH1A1 (0.37) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL22879866 0.88 MEN1 (0.43) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL22880203 0.85 MAPT (0.37) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL22880443 0.84 MAPT (0.36) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL22880081 0.83 MEN1 (0.37) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL22879960 0.83 MEN1 (0.37) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL22879869 0.83 F9 (0.35) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL22276573 0.83 MEN1 (0.43) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL22096950 0.83 MEN1 (0.36) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL22880431 0.82 MAPT (0.36) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345827-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-10-26 US disclosed
US-20230345827-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-10-26 US disclosed
US-11793075-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-17 US disclosed
US-11793075-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-17 US disclosed
US-20230126428-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-04-27 US disclosed
US-20230126428-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-04-27 US disclosed
US-11552257-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-01-10 US disclosed
US-20220131081-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-04-28 US disclosed
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-01-28 US disclosed
US-20210020849-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-21 US disclosed
US-20210013427-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, LIMS1 ALDH1A1 487/4885MAPT 1849/4885KDM4E 3066/4885
US-20220131081-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LEF1, ODC1, TMEM109 ALDH1A1 45/4885MAPT 2469/4885KDM4E 2206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.