SCHEMBL2288019

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2290436	0.90	MAPT (0.40)	CDK4CCND1MAPTMAPK1NPSR1
	SCHEMBL1539444	0.85	RXRA (0.49)	CDK4CCND1MAPTMAPK1NPSR1
	SCHEMBL2294685	0.81	ALDH1A1 (0.36)	CDK4CCND1MAPTALDH1A1SMN1; SMN2
	SCHEMBL2289307	0.80	ALDH1A1 (0.44)	MAPTMAPK1NPSR1ALDH1A1SMN1; SMN2
	SCHEMBL1539554	0.79	APP (0.45)	SMN1; SMN2HTTKMT2AL3MBTL1NPC1
	SCHEMBL2286460	0.78	SOD1 (0.51)	CDK4CCND1MAPTHTTTDP1
	SCHEMBL2291400	0.76	ALDH1A1 (0.39)	CDK4CCND1ALDH1A1SMN1; SMN2HTT
	SCHEMBL8684021	0.74	MRGPRX4 (0.48)	CDK4CCND1MAPTMAPK1SMN1; SMN2
	SCHEMBL1539454	0.72	HPGD (0.52)	CDK4CCND1MAPTNPSR1ALDH1A1
	Ethylene Glycol SCHEMBL1683294	0.72	RXRA (0.40)	CDK4CCND1MAPTMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.