Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.59 |
| ▸ | TYMP | P19971 | 3/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 2/20 | 0.55 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.51 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.51 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25098352 | 0.91 | ADORA3 (0.59) | P2RX3TYMPPAX8GSK3ARPS6KA3 | |
| SCHEMBL9132895 | 0.91 | ADORA3 (0.59) | P2RX3TYMPPAX8GSK3ARPS6KA3 | |
| SCHEMBL8629175 | 0.91 | ADORA3 (0.59) | P2RX3TYMPPAX8GSK3ARPS6KA3 | |
| Inosine SCHEMBL12964365 | 0.90 | PAX8 (0.69) | P2RX3TYMPPAX8GSK3ARPS6KA3 | |
| Inosine SCHEMBL13320592 | 0.90 | PAX8 (0.69) | P2RX3TYMPPAX8GSK3ARPS6KA3 | |
| Inosine SCHEMBL16707275 | 0.90 | PAX8 (0.69) | P2RX3TYMPPAX8GSK3ARPS6KA3 | |
| Inosine SCHEMBL13012212 | 0.90 | PAX8 (0.69) | P2RX3TYMPPAX8GSK3ARPS6KA3 | |
| Inosine SCHEMBL1738548 | 0.90 | PAX8 (0.69) | P2RX3TYMPPAX8GSK3ARPS6KA3 | |
| Inosine SCHEMBL6933022 | 0.90 | PAX8 (0.69) | P2RX3TYMPPAX8GSK3ARPS6KA3 | |
| Inosine SCHEMBL10001664 | 0.90 | PAX8 (0.69) | P2RX3TYMPPAX8GSK3ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220008549-A1 | NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-01-13 | — | — | US | disclosed |
| US-20210009630-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220008549-A1 | NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF | STING1, CGAS, TLR9 | P2RX3 220/4885TYMP 1536/4885PAX8 3735/4885 |
| US-20210009630-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | STING1, CGAS, IFNAR1 | P2RX3 46/4885TYMP 1289/4885PAX8 4374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.