Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.59 |
| ▸ | PDE2A | O00408 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TYMP | P19971 | 2/20 | 0.54 |
| ▸ | GSK3A | P49840 | 2/20 | 0.52 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132895 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AADORA1PDE2AADRA1A | |
| SCHEMBL8629175 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AADORA1PDE2AADRA1A | |
| SCHEMBL22883167 | 0.91 | P2RX3 (0.59) | ADORA3ADORA2AADORA1PDE2AADRA1A | |
| SCHEMBL23786487 | 0.90 | P2RX3 (0.56) | ADORA3ADORA2AADORA1PDE2AADRA1A | |
| Inosine SCHEMBL13320592 | 0.90 | PAX8 (0.69) | ADORA3ADORA2AADORA1P2RX3PAX8 | |
| Inosine SCHEMBL6933022 | 0.90 | PAX8 (0.69) | ADORA3ADORA2AADORA1P2RX3PAX8 | |
| Inosine SCHEMBL12964365 | 0.90 | PAX8 (0.69) | ADORA3ADORA2AADORA1P2RX3PAX8 | |
| Inosine SCHEMBL10001664 | 0.90 | PAX8 (0.69) | ADORA3ADORA2AADORA1P2RX3PAX8 | |
| Inosine SCHEMBL13012212 | 0.90 | PAX8 (0.69) | ADORA3ADORA2AADORA1P2RX3PAX8 | |
| Inosine SCHEMBL1738548 | 0.90 | PAX8 (0.69) | ADORA3ADORA2AADORA1P2RX3PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155418-A9 | MODIFIED OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |