Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | F10 | P00742 | 4/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.43 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22885968 | 0.90 | DCAF1 (0.49) | DCAF1PYGLF2F10PRSS1 | |
| SCHEMBL22897214 | 0.87 | DCAF1 (0.51) | DCAF1PYGLF2F10PRSS1 | |
| SCHEMBL20028717 | 0.86 | DCAF1 (0.50) | DCAF1PYGLF2F10PRSS1 | |
| SCHEMBL20027723 | 0.82 | PYGL (0.52) | DCAF1PYGLF2F10PRSS1 | |
| SCHEMBL22897243 | 0.81 | DCAF1 (0.51) | DCAF1PYGLCTSVCTSLCTSS | |
| SCHEMBL20027718 | 0.81 | DCAF1 (0.51) | DCAF1PYGLCTSVCTSLCTSS | |
| SCHEMBL20027914 | 0.81 | DCAF1 (0.48) | DCAF1PYGLKMT2A | |
| SCHEMBL22886627 | 0.81 | PYGL (0.48) | DCAF1PYGLF2F10PRSS1 | |
| SCHEMBL22886540 | 0.79 | PYGL (0.44) | DCAF1PYGL | |
| SCHEMBL20027617 | 0.78 | PYGL (0.43) | DCAF1PYGLCTSVCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009564-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPERTICS INC (US) | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009564-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | CAPNS1, CAPN9, CAPN1 | DCAF1 2355/4885PYGL 719/4885F2 4704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.