Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453984 | 0.82 | ALDH1A1 (0.49) | RAB9AMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL22890213 | 0.80 | TDP1 (0.42) | RAB9AMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL7945840 | 0.79 | RAB9A (0.70) | RAB9AMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL20695012 | 0.78 | RAB9A (0.60) | RAB9AMEN1KMT2AALDH1A1POLB | |
| SCHEMBL19678705 | 0.77 | RAB9A (0.61) | RAB9AMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL20695013 | 0.75 | RAB9A (0.56) | RAB9AMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL11376580 | 0.75 | TDP1 (0.60) | RAB9AMEN1KMT2AALDH1A1POLB | |
| SCHEMBL28323455 | 0.75 | RAB9A (0.59) | RAB9AMEN1KMT2AALDH1A1POLB | |
| SCHEMBL8723076 | 0.75 | TDP1 (0.51) | RAB9AMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL22890345 | 0.74 | TDP1 (0.50) | RAB9AMEN1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007477-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | E-SCAPE BIO, INC. (US) | 2021-01-14 | — | — | WO | disclosed |