Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.70 |
| ▸ | NPC1 | O15118 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28317903 | 0.92 | RAB9A (0.67) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL7606037 | 0.86 | NPC1 (0.61) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL1083061 | 0.82 | RAB9A (0.74) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL6940724 | 0.81 | MEN1 (0.61) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL3636008 | 0.80 | NPC1 (0.65) | RAB9ANPC1PTGS2ALDH1A1CYP3A4 | |
| SCHEMBL18229478 | 0.80 | NPC1 (0.70) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL22890769 | 0.79 | RAB9A (0.57) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL6035984 | 0.79 | NPC1 (0.53) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL5584124 | 0.78 | NPC1 (0.61) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL6797269 | 0.77 | NPC1 (0.56) | RAB9ANPC1PTGS2CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218193-A | 3- hydroxyquinazoline -2,4 (1H, 3H)-diketone derivative and the preparation method and application thereof | 山东大学 | 2019-09-10 | — | — | CN | disclosed |
| US-6274383-B1 | REACTING AN AMINO BOUND TO A SOLID SUPPORT WITH AN ISATOIC ANHYDRIDE TO FORM A 2-AMINOBENZAMIDE BOUND TO THE SUPPORT, AND THEN REACTING WITH ALDEHYDE USING A LEWIS ACID CATALYST TO FORM A 2,3-DIHYDRO-4(1H)-QUINAZOLINONE BOUND TO SUPPORT | SEPRACOR INC. | 2001-08-14 | — | — | US | disclosed |