SCHEMBL22891526

SCHEMBL22891526

CC1(C)c2ccccc2-c2cc(N3c4ccccc4C4(c5ccccc5-c5ccccc54)c4ccc(Nc5ccccc5)cc43)ccc21

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 1/20 0.38
▸ PGR P06401 9/20 0.36
▸ GNG2 P59768 1/20 0.34
▸ GNB1 P62873 1/20 0.34
▸ APP P05067 1/20 0.33
▸ HSP90AA1 P07900 1/20 0.33
▸ MARK3 P27448 1/20 0.32
▸ PTH1R Q03431 1/20 0.32
▸ TNK2 Q07912 3/20 0.31
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ GFER P55789 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22891764 0.87 GNG2 (0.45) PDK2PGRGNG2GNB1APP
SCHEMBL22891670 0.85 ALDH1A1 (0.46) PDK2PGRGNG2GNB1APP
SCHEMBL22891640 0.85 PDK2 (0.40) PDK2PGRGNG2GNB1APP
SCHEMBL22891468 0.84 PDK2 (0.43) PDK2PGRGNG2GNB1APP
SCHEMBL24646447 0.83 PGR (0.37) PDK2PGRMEN1KMT2A
SCHEMBL14838256 0.83 PGR (0.37) PDK2PGRMEN1KMT2A
SCHEMBL22891638 0.82 PDK2 (0.40) PDK2PGRGNG2GNB1APP
SCHEMBL22891510 0.82 PDK2 (0.38) PDK2PGRAPPTNK2MEN1
SCHEMBL24027645 0.81 PGR (0.47) PDK2PGRGNG2GNB1APP
SCHEMBL26574674 0.80 PDK2 (0.48) PDK2APPMEN1KMT2AGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3764416-B1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO LTD (KR) 2022-01-26 — — EP disclosed
US-20210013420-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2021-01-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210013420-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF PIEZO1, ORAI2, OR10J3 PDK2 2546/4885PGR 2596/4885GNG2 2366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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