Phosphoric Acid

Phosphoric Acid

SCHEMBL2289263

O=C1NC(=O)c2c1ccc1ccccc21.O=P(O)(O)O

nearest known ligand 0.46

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Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 4/20 0.46
DNMT1 P26358 1/20 0.46
KMT2A Q03164 5/20 0.45
MEN1 O00255 4/20 0.45
CYP1A2 P05177 3/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 2/20 0.44
CYP2C19 P33261 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
HTT P42858 1/20 0.44
CDK5 Q00535 1/20 0.44
CDK5R1 Q15078 1/20 0.44
NCOA1 Q15788 1/20 0.44
NCOA3 Q9Y6Q9 1/20 0.44
CDK4 P11802 2/20 0.42
CCND1 P24385 2/20 0.42
GSK3B P49841 2/20 0.42
CCNB2 O95067 1/20 0.42
CCNE2 O96020 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57037 0.91 DNMT1 (0.53) PARP1DNMT1KMT2AMEN1CYP1A2
SCHEMBL7486488 0.90 DNMT1 (0.52) PARP1DNMT1KMT2AMEN1CYP1A2
SCHEMBL11542348 0.90 DNMT1 (0.52) PARP1DNMT1KMT2AMEN1CYP1A2
Carbamic Acid SCHEMBL17558332 0.85 WDR5 (0.46) PARP1DNMT1KMT2AMEN1CYP1A2
SCHEMBL217014 0.84 DNMT1 (0.47) PARP1DNMT1KMT2AMEN1CYP1A2
SCHEMBL7171073 0.84 DNMT1 (0.47) PARP1DNMT1KMT2AMEN1CYP1A2
SCHEMBL5397675 0.83 CYP1A2 (0.57) PARP1DNMT1KMT2AMEN1CYP1A2
SCHEMBL218236 0.80 SMN1; SMN2 (0.46) PARP1DNMT1KMT2AMEN1CYP1A2
Trifluoromethanesulfonic Acid SCHEMBL6306910 0.80 DNMT1 (0.44) PARP1DNMT1KMT2AMEN1CYP1A2
SCHEMBL8815705 0.77 PARP1 (0.52) PARP1DNMT1KMT2AMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104920448-B Naphthalimide potassium phosphate plant growth regulator and application thereof 青岛科技大学 2017-05-03 CN claimed
CN-104920448-A Naphthalimide potassium phosphate plant growth regulator and application thereof UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-09-23 CN claimed
CN-104920448-B Naphthalimide potassium phosphate plant growth regulator and application thereof 青岛科技大学 2017-05-03 CN disclosed
US-9631219-B2 Metabolic rate indicator for cellular populations NALCO COMPANY (US) 2017-04-25 US disclosed
CN-105646347-A Naphthalimide aryl urea compound and application thereof 青岛科技大学 2016-06-08 CN disclosed
CN-104920448-A Naphthalimide potassium phosphate plant growth regulator and application thereof UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-09-23 CN disclosed
WO-2011106363-A2 METABOLIC RATE INDICATOR FOR CELLULAR POPULATIONS NALCO COMPANY (US) 2011-09-01 WO disclosed
US-20110207111-A1 METABOLIC RATE INDICATOR FOR CELLULAR POPULATIONS ECOLAB USA INC. 2011-08-25 US disclosed