Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24310936 | 1.00 | EPHX2 (0.40) | EPHX2RAB9ANPC1EPHX1KDM1A | |
| SCHEMBL22893113 | 1.00 | EPHX2 (0.40) | EPHX2RAB9ANPC1EPHX1KDM1A | |
| SCHEMBL18401356 | 1.00 | EPHX2 (0.40) | EPHX2RAB9ANPC1EPHX1KDM1A | |
| SCHEMBL22906294 | 1.00 | EPHX2 (0.40) | EPHX2RAB9ANPC1EPHX1KDM1A | |
| SCHEMBL5020562 | 1.00 | EPHX2 (0.40) | EPHX2RAB9ANPC1EPHX1KDM1A | |
| SCHEMBL10037070 | 0.98 | EPHX2 (0.37) | EPHX2RAB9ANPC1EPHX1KDM1A | |
| Iodide SCHEMBL2647139 | 0.96 | EPHX2 (0.36) | EPHX2RAB9ANPC1EPHX1KDM1A | |
| SCHEMBL5519016 | 0.89 | GBA1 (0.34) | SIGMAR1OPRM1OPRD1OPRK1 | |
| Bromide SCHEMBL28426746 | 0.87 | GBA1 (0.33) | SIGMAR1 | |
| SCHEMBL15593375 | 0.80 | ACHE (0.38) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230301300-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2023-09-28 | — | — | US | disclosed |
| US-20220281837-A1 | SUBSTITUTED PYRIDAZINONES AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2022-09-08 | — | — | US | disclosed |
| US-20210009530-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009530-A1 | HERBICIDAL COMPOUNDS | DDT, HPD, PGD | EPHX2 230/4885RAB9A 4008/4885NPC1 4799/4885 |
| US-20230301300-A1 | HERBICIDAL COMPOSITIONS | GMDS, DDT, AADAC | EPHX2 680/4885RAB9A 4007/4885NPC1 4842/4885 |
| US-20220281837-A1 | SUBSTITUTED PYRIDAZINONES AS HERBICIDES | PDXK, HPD, DDT | EPHX2 397/4885RAB9A 4174/4885NPC1 4867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.