Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380003 | 0.85 | NPC1 (0.58) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL25394296 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL6590835 | 0.78 | MAOB (0.45) | KDM4EALDH1A1PARP1MAPTLMNA | |
| SCHEMBL1071182 | 0.78 | DAO (0.58) | CA1PARP1NPSR1SMN1; SMN2PSMB8 | |
| SCHEMBL1500233 | 0.78 | METAP2 (0.43) | NPSR1OGTNOS1NOS3NOS2 | |
| SCHEMBL2289312 | 0.78 | NOS1 (0.62) | KDM4EALDH1A1HPGDGAAPARP1 | |
| SCHEMBL118727 | 0.77 | NOS1 (0.61) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL1937499 | 0.74 | RAB9A (0.69) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL31613986 | 0.74 | RAB9A (0.69) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL2284104 | 0.74 | KDM4E (0.57) | KDM4EALDH1A1HPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585873-B1 | Method of preparing disazo pigments | CLARIANT GMBH (DE) | 1997-12-29 | — | — | EP | disclosed |
| US-5559216-A | AZO COUPLING | HOECHST AG (DE) | 1996-09-24 | — | — | US | disclosed |
| US-5493011-A | PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS | HOECHST AG (DE) | 1996-02-20 | — | — | US | disclosed |
| EP-0585873-A1 | Method of preparing disazo pigments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-09 | — | — | EP | disclosed |
| EP-0316649-B1 | WATER INSOLUBLE AZO COLOURING AGENTS, THEIR PREPARATION AND USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-22 | — | — | EP | disclosed |