SCHEMBL22893783

SCHEMBL22893783

c1ccc(-c2nc(-c3ccc4c(ccc5oc6ccccc6c54)c3)nc(-n3c4ccccc4c4cc(-c5ccc(N(c6ccccc6)c6ccccc6)cc5)ccc43)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.33
PGR P06401 1/20 0.33
PLA2G2A P14555 1/20 0.32
PLA2G4A P47712 1/20 0.32
FAAH O00519 1/20 0.31
PTGES O14684 1/20 0.30
CASP3 P42574 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22893815 0.93 PTGES (0.34) TSPOPGRPTGES
SCHEMBL22893781 0.90 PGR (0.34) TSPOPGRPLA2G2APLA2G4ACASP3
SCHEMBL22893871 0.89 PGR (0.34) TSPOPGRPLA2G2APLA2G4ACASP3
SCHEMBL22893995 0.88 ABCG2 (0.32)
SCHEMBL15763820 0.88 TSPO (0.35) TSPOPLA2G2APLA2G4A
SCHEMBL22893758 0.87 TSPO (0.32) TSPO
SCHEMBL22893872 0.86 PGR (0.33) PGRPLA2G2APLA2G4A
SCHEMBL22894000 0.86 CYP1A2 (0.31)
SCHEMBL23308309 0.85 TSPO (0.42) TSPO
SCHEMBL17251500 0.85 TSPO (0.42) TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210013411-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2021-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210013411-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1A1, CYP1B1 TSPO 2365/4885PGR 1594/4885PLA2G2A 4090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.