Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | LPL | P06858 | 2/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13746337 | 0.87 | PLK1 (0.51) | PLK1ALDH1A1THRBL3MBTL1POLB | |
| SCHEMBL21699897 | 0.86 | CYP3A4 (0.53) | CA2PLK1ALDH1A1HSD17B10TP53 | |
| SCHEMBL13747158 | 0.84 | PLK1 (0.45) | CA2LPLLIPGPLK1ALDH1A1 | |
| SCHEMBL20852371 | 0.80 | LPL (0.48) | CA2LPLLIPGMGLLPLK1 | |
| SCHEMBL8267536 | 0.80 | PLAU (0.52) | CA2LPLLIPGMGLLPLK1 | |
| SCHEMBL142480 | 0.79 | LPL (0.62) | CA2LPLLIPGMGLLPLK1 | |
| SCHEMBL18688625 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TP53TSHRMAPK1 | |
| SCHEMBL9218575 | 0.77 | ALDH1A1 (0.52) | PLK1ALDH1A1HSD17B10TP53TSHR | |
| SCHEMBL23142745 | 0.76 | LPL (0.45) | CA2LPLLIPGMGLLPLK1 | |
| SCHEMBL8423871 | 0.76 | NOS3 (0.55) | CA2ALDH1A1TP53TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270573-B1 | Xanthine and phenazone acesulfam-H complexes with improved taste, process for their preparation and their use | NUTRINOVANUTRITION SPECIALTIES (DE) | 2004-09-01 | — | — | EP | claimed |
| EP-1270573-A1 | Xanthine and phenazone acesulfam-H complexes with improved taste, process for their preparation and their use | Nutrinova Nutrition Specialties & Food Ingredients GmbH (DE) | 2003-01-02 | — | — | EP | claimed |
| WO-1998052616-A2 | NONSTEROIDAL ANTIRHEUMATIC AGENTS OR THROMBOCYTE-AGGLUTINATION INHIBITORS TO IMPROVE REPRESENTATION OF VESSELS, LYMPH NODES AND BONE MARROW WITH PHARMACEUTICAL PREPARATIONS CONTAINING PARTICLES, VESICLES OF POLYMERS | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 1998-11-26 | — | — | WO | claimed |
| EP-4212181-A2 | METHYLENE CARBAMATE LINKERS FOR USE WITH TARGETED-DRUG CONJUGATES | Seagen Inc. (US) | 2023-07-19 | — | — | EP | disclosed |
| WO-2023083919-A1 | CONJUGATES COMPRISING A PHOSPHORUS (V) AND A CAMPTOTHECIN MOIETY | TUBULIS GMBH (DE) | 2023-05-19 | — | — | WO | disclosed |
| WO-2021067861-A1 | CAMPTOTHECIN PEPTIDE CONJUGATES | SEAGEN INC. (US) | 2021-04-08 | — | — | WO | disclosed |
| EP-3756663-A1 | PEGYLATED DRUG-LINKERS FOR IMPROVED LIGAND-DRUG CONJUGATE PHARMACOKINETICS | Seagen Inc. (US) | 2020-12-30 | — | — | EP | disclosed |
| EP-3057585-B1 | PEGYLATED DRUG-LINKERS FOR IMPROVED LIGAND-DRUG CONJUGATE PHARMACOKINETICS | SEATTLE GENETICS INC (US) | 2020-07-22 | — | — | EP | disclosed |
| EP-3281643-A2 | RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE | Kyungpook National University Industry-Academic Cooperation Foundation (KR) | 2018-02-14 | — | — | EP | disclosed |
| US-9688617-B2 | Photoreactive synthetic regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-06-27 | — | — | US | disclosed |
| WO-2017020972-A1 | PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES | VAN BERKEL, Patricius Hendrikus Cornelis (CH) | 2017-02-09 | — | — | WO | disclosed |
| EP-1270573-B1 | Xanthine and phenazone acesulfam-H complexes with improved taste, process for their preparation and their use | NUTRINOVANUTRITION SPECIALTIES (DE) | 2004-09-01 | — | — | EP | disclosed |
| EP-0475160-B2 | Preparation for drug application in minute droplet form | IDEA AG (DE) | 2004-07-14 | — | — | EP | disclosed |
| EP-1270573-A1 | Xanthine and phenazone acesulfam-H complexes with improved taste, process for their preparation and their use | Nutrinova Nutrition Specialties & Food Ingredients GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-6165500-A | Preparation for the application of agents in mini-droplets | IDEA AG (DE) | 2000-12-26 | — | — | US | disclosed |
| WO-1998052616-A2 | NONSTEROIDAL ANTIRHEUMATIC AGENTS OR THROMBOCYTE-AGGLUTINATION INHIBITORS TO IMPROVE REPRESENTATION OF VESSELS, LYMPH NODES AND BONE MARROW WITH PHARMACEUTICAL PREPARATIONS CONTAINING PARTICLES, VESICLES OF POLYMERS | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 1998-11-26 | — | — | WO | disclosed |
| EP-0475160-B1 | Preparation for drug application in minute droplet form | IDEA AG (DE) | 1996-02-14 | — | — | EP | disclosed |
| EP-0475160-A1 | Preparation for drug application in minute droplet form | Cevc, Gregor, Prof. Dr. (DE) | 1992-03-18 | — | — | EP | disclosed |
| WO-1992003122-A1 | PREPARATION FOR APPLICATION OF ACTIVE SUBSTANCES IN THE FORM OF MINIMUM-SIZED DROPLETS | CEVC GREGOR (DE) | 1992-03-05 | — | — | WO | disclosed |
| EP-0007572-B1 | PHARMACEUTICAL MIXTURES CONTAINING AN AMANTADINE COMPOUND | CIBA-GEIGY AG (CH) | 1983-04-27 | — | — | EP | disclosed |