Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289401 | 0.87 | CA2 (0.47) | PLK1THRBCNR2L3MBTL1GAA | |
| SCHEMBL9861628 | 0.87 | PLK1 (0.64) | PLK1THRBCNR2L3MBTL1GAA | |
| SCHEMBL13747158 | 0.83 | PLK1 (0.45) | PLK1THRBL3MBTL1GAAALDH1A1 | |
| SCHEMBL6038454 | 0.80 | ADRA2A (0.56) | ALDH1A1KMT2AMAPTLMNAADRA2A | |
| SCHEMBL27449104 | 0.79 | ALDH1A1 (0.64) | PLK1THRBCNR2L3MBTL1GAA | |
| SCHEMBL4605419 | 0.79 | L3MBTL1 (0.58) | PLK1THRBCNR2L3MBTL1GAA | |
| Benzophenone SCHEMBL28417175 | 0.79 | L3MBTL1 (0.58) | PLK1THRBCNR2L3MBTL1GAA | |
| SCHEMBL9099918 | 0.78 | PLK1 (0.55) | PLK1THRBCNR2L3MBTL1GAA | |
| SCHEMBL31164297 | 0.78 | POLB (0.72) | PLK1THRBCNR2L3MBTL1GAA | |
| SCHEMBL28927088 | 0.76 | PLK1 (0.53) | PLK1THRBCNR2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576245-B2 | Fluorous tagging and scavenging reactants and methods of synthesis and use thereof | FLUOROUS TECHNOLOGIES INCORPORATED (US) | 2009-08-18 | — | — | US | disclosed |