Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA4 | P22748 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231210 | 0.85 | CA2 (0.48) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL29760 | 0.83 | ACHE (0.36) | ACHE | |
| SCHEMBL943918 | 0.77 | CA2 (0.41) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL2289380 | 0.76 | CA2 (0.40) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL2285289 | 0.76 | CA2 (0.40) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL20476840 | 0.76 | TPMT (0.43) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL4158740 | 0.74 | ACHE (0.41) | CA2CA4CA1ACHE | |
| SCHEMBL5475365 | 0.73 | TDP1 (0.39) | CA2CA1PTPN1ACHE | |
| SCHEMBL2284682 | 0.73 | ACHE (0.30) | ACHE | |
| SCHEMBL2286065 | 0.73 | KDM4E (0.31) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989394-B2 | Substituted 1-(azolin-2-yl)-amino-2-aryl-1-hetaryl-ethane compounds | BASF SE (DE) | 2011-08-02 | — | — | US | disclosed |
| US-20090131256-A1 | Substituted 1-(azolin-2-yl)-amino-2-aryl-1-hetaryl-ethane Compounds | BASF SE (DE) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131256-A1 | Substituted 1-(azolin-2-yl)-amino-2-aryl-1-hetaryl-ethane Compounds | AAAS, AIPL1, ATXN2 | CA2 1194/4885CA4 3404/4885CA1 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.