Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18788926 | 0.87 | GAA (0.35) | GAASMN1; SMN2KMT2AKCNQ2MEN1 | |
| SCHEMBL2292533 | 0.84 | TSPO (0.33) | TSPOGAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2292527 | 0.76 | ALOX5 (0.48) | TSPOGAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2291992 | 0.74 | AKR1B1 (0.39) | TSPOGAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2291776 | 0.70 | MAPK1 (0.41) | TSPOGAASMN1; SMN2HTTKDM4E | |
| Sulfuric Acid SCHEMBL29282027 | 0.69 | GAA (0.36) | TSPOGAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2287889 | 0.69 | GAA (0.48) | TSPOGAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3413314 | 0.69 | LTB4R (0.40) | GAASMN1; SMN2 | |
| SCHEMBL2292134 | 0.68 | S1PR5 (0.41) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL17187689 | 0.68 | CYP2C19 (0.46) | GAASMN1; SMN2KMT2AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232830-B | Method for measuring dehydrogenase and substrate concentration thereof, electron mediator, dehydrogenase containing the electron mediator, and reagent for measuring substrate thereof | 株式会社同仁化学研究所 | 2020-02-14 | — | — | CN | disclosed |
| US-10287619-B2 | Measurement method for dehydrogenase and substrate concentration thereof, electron mediator, and measurement reagent for dehydrogenase including said electron mediator and for substrate thereof | DOJINDO LABORATORIES (JP) | 2019-05-14 | — | — | US | disclosed |
| US-20170121753-A1 | MEASUREMENT METHOD FOR DEHYDROGENASE AND SUBSTRATE CONCENTRATION THEREOF, ELECTRON MEDIATOR, AND MEASUREMENT REAGENT FOR DEHYDROGENASE INCLUDING SAID ELECTRON MEDIATOR AND FOR SUBSTRATE THEREOF | DOJINDO LABORATORIES (JP) | 2017-05-04 | — | — | US | disclosed |
| CN-106232830-A | Dehydrogenase and the assay method of substrate concentration thereof, Problem of Electronic Broker and the dehydrogenase and the substrate thereof that comprise this Problem of Electronic Broker measure reagent | 株式会社同仁化学研究所 | 2016-12-14 | — | — | CN | disclosed |
| EP-2265726-B1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIAGNOSTICS GMBH (DE) | 2014-05-07 | — | — | EP | disclosed |
| US-8535511-B2 | Methods for electrochemical analysis using matrix compositions with alkylphenazine quaternary salt and a nitrosoaniline | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-8008037-B2 | Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20090246808-A1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIABETES CARE, INC. | 2009-10-01 | — | — | US | disclosed |