Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3413314 | 0.84 | LTB4R (0.40) | GAASMN1; SMN2 | |
| Sulfuric Acid SCHEMBL29282027 | 0.82 | GAA (0.36) | GAASMN1; SMN2TSPOKMT2AMEN1 | |
| SCHEMBL2292527 | 0.81 | ALOX5 (0.48) | GAASMN1; SMN2TDP1TSPOKMT2A | |
| SCHEMBL2292134 | 0.75 | S1PR5 (0.41) | SMN1; SMN2TDP1KMT2AMEN1PLA2G2A | |
| SCHEMBL17187689 | 0.75 | CYP2C19 (0.46) | GAASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL2291776 | 0.75 | MAPK1 (0.41) | GAASMN1; SMN2TSPOKDM4EBRD4 | |
| SCHEMBL2287889 | 0.74 | GAA (0.48) | GAASMN1; SMN2TDP1TSPOKMT2A | |
| SCHEMBL2289464 | 0.74 | TSPO (0.35) | GAASMN1; SMN2TSPOKMT2AKDM4E | |
| SCHEMBL8376596 | 0.71 | DRD2 (0.39) | KMT2AKDM4EMEN1 | |
| Sulfuric Acid SCHEMBL10339576 | 0.71 | ALDH1A1 (0.38) | GAASMN1; SMN2TDP1TSPOKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265726-B1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIAGNOSTICS GMBH (DE) | 2014-05-07 | — | — | EP | disclosed |
| US-8535511-B2 | Methods for electrochemical analysis using matrix compositions with alkylphenazine quaternary salt and a nitrosoaniline | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-8008037-B2 | Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| EP-2265726-A1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | Roche Diagnostics GmbH (DE) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009118157-A1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIAGNOSTICS GMBH (DE) | 2009-10-01 | — | — | WO | disclosed |
| US-20090246808-A1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIABETES CARE, INC. | 2009-10-01 | — | — | US | disclosed |