Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28718728 | 0.76 | TP53 (0.47) | TP53KDM4ECASP6SHBGTTR | |
| SCHEMBL31618879 | 0.76 | TP53 (0.47) | TP53KDM4ECASP6SHBGTTR | |
| SCHEMBL28419431 | 0.73 | TP53 (0.42) | TP53KDM4ECASP6SHBGTTR | |
| SCHEMBL2123178 | 0.72 | TTR (0.46) | TP53KDM4ECASP6SHBGTTR | |
| SCHEMBL2120863 | 0.71 | TTR (0.59) | TP53KDM4ECASP6SHBGTTR | |
| SCHEMBL12817414 | 0.71 | TTR (0.50) | TP53KDM4ETTRTPMT | |
| SCHEMBL15360551 | 0.69 | TTR (0.41) | TP53KDM4ETTRTPMT | |
| SCHEMBL29425551 | 0.68 | TTR (0.42) | TP53TTRTPMT | |
| SCHEMBL2370163 | 0.68 | TTR (0.42) | TP53TTRTPMT | |
| SCHEMBL23921940 | 0.68 | TP53 (0.41) | TP53KDM4ECASP6SHBGTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11744916-B2 | Radiopaque polymers | BIOCOMPATIBLES UK LIMITED | 2023-09-05 | — | — | US | disclosed |
| US-20210015963-A1 | RADIOPAQUE POLYMERS | BIOCOMPATIBLES UK LTD. (GB) | 2021-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210015963-A1 | RADIOPAQUE POLYMERS | TPO, PGLS, IQGAP1 | TP53 823/4885KDM4E 1566/4885CASP6 3342/4885 |
| US-11744916-B2 | Radiopaque polymers | TPO, PGLS, IQGAP1 | TP53 823/4885KDM4E 1566/4885CASP6 3342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.