Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29425551 | 1.00 | TTR (0.42) | TTRTP53SLC6A4ERN1SLC6A2 | |
| 2,3,5-Triiodobenzoic Acid SCHEMBL9324434 | 0.83 | TPMT (0.38) | TTRTP53TPMT | |
| SCHEMBL25338439 | 0.81 | TTR (0.39) | TTR | |
| SCHEMBL2120863 | 0.78 | TTR (0.59) | TTRTP53SLC6A4ERN1SLC6A2 | |
| SCHEMBL25361257 | 0.78 | TTR (0.36) | TTR | |
| SCHEMBL19880768 | 0.76 | TTR (0.44) | TTRTP53SLC6A4SLC6A2CYP1A2 | |
| SCHEMBL26036410 | 0.76 | SHBG (0.36) | TTRTP53SLC6A4SLC6A2 | |
| SCHEMBL13928917 | 0.76 | TTR (0.39) | TTRTP53SLC6A4 | |
| SCHEMBL20670556 | 0.76 | TTR (0.39) | TTRTP53SLC6A4SLC6A2 | |
| SCHEMBL28879893 | 0.75 | IDO1 (0.39) | TTRTP53SLC6A4ERN1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805644-B | Nontransmissive polymer and preparation method and application thereof | 苏州美创医疗科技有限公司 | 2022-09-16 | — | — | CN | claimed |
| CN-114805644-A | Nontransmissive polymer and preparation method and application thereof | 苏州美创医疗科技有限公司 | 2022-07-29 | — | — | CN | claimed |
| EP-2968618-B1 | IMAGEABLE EMBOLIC MICROSPHERE | BIOCOMPATIBLES UK LTD (GB) | 2021-02-17 | — | — | EP | claimed |
| CN-110372484-B | Radiopaque polyvinyl alcohol microspheres | 赵修文 | 2020-05-22 | — | — | CN | claimed |
| CN-110372484-A | A kind of radiopaque polyvinyl alcohol microparticles | 赵修文 | 2019-10-25 | — | — | CN | claimed |
| CN-105517580-A | Imageable embolic microspheres | DREHER MATTHEW R | 2016-04-20 | — | — | CN | claimed |
| US-20160030602-A1 | IMAGEABLE EMBOLIC MICROSPHERE | Boston Scientific Medical Device Limited (IE) | 2016-02-04 | — | — | US | claimed |
| EP-2968618-A2 | IMAGEABLE EMBOLIC MICROSPHERE | Dreher, Matthew R. (US) | 2016-01-20 | — | — | EP | claimed |
| WO-2014152488-A2 | IMAGEABLE EMBOLIC MICROSPHERE | DREHER MATTHEW R (US) | 2014-09-25 | — | — | WO | claimed |
| EP-0578765-A1 | DELIVERY OF X-RAY CONTRAST AGENTS USING RECEPTOR MEDIATED ENDOCYTOSIS | ADVANCED MAGNETICS INCORPORATED (US) | 1994-01-19 | — | — | EP | claimed |
| WO-1992017216-A1 | DELIVERY OF X-RAY CONTRAST AGENTS USING RECEPTOR MEDIATED ENDOCYTOSIS | ADVANCED MAGNETICS, INC. (US) | 1992-10-15 | — | — | WO | claimed |
| US-5141739-A | Delivery of x-ray contrast agents using receptor mediated endocytosis | ADVANCED MAGNETICS, INC. (US) | 1992-08-25 | — | — | US | claimed |
| US-20240325573-A1 | X-RAY DEVELOPABLE MOLECULE, EMBOLISM MICROSPHERE AND PREPARATION METHODS THEREFOR | SHANGHAI HUIHE HEALTHCARE TECHNOLOGY CO., LTD. (CN) | 2024-10-03 | — | — | US | disclosed |
| CN-117982687-A | Imageable embolic microspheres | 生物兼容英国有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-11957755-B2 | Radiopaque polymers | Boston Scientific Medical Device Limited (IE) | 2024-04-16 | — | — | US | disclosed |
| CN-117586440-B | Iodinated polyhydroxy polymer, preparation method and liquid embolic agent prepared from iodinated polyhydroxy polymer | 苏州美创医疗科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| US-20050036946-A1 | Radio-opaque compounds, compositions containing same and methods of their synthesis and use | PATHAK HOLDINGS, LLC | 2005-02-17 | — | — | US | disclosed |
| EP-0578765-A1 | DELIVERY OF X-RAY CONTRAST AGENTS USING RECEPTOR MEDIATED ENDOCYTOSIS | ADVANCED MAGNETICS INCORPORATED (US) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017216-A1 | DELIVERY OF X-RAY CONTRAST AGENTS USING RECEPTOR MEDIATED ENDOCYTOSIS | ADVANCED MAGNETICS, INC. (US) | 1992-10-15 | — | — | WO | disclosed |
| US-5141739-A | Delivery of x-ray contrast agents using receptor mediated endocytosis | ADVANCED MAGNETICS, INC. (US) | 1992-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240325573-A1 | X-RAY DEVELOPABLE MOLECULE, EMBOLISM MICROSPHERE AND PREPARATION METHODS THEREFOR | F11, FAR1, FGB | TTR 3091/4885TP53 1579/4885SLC6A4 4453/4885 |
| US-20160030602-A1 | IMAGEABLE EMBOLIC MICROSPHERE | MKI67, PCNA, VHL | TTR 3855/4885TP53 28/4885SLC6A4 3113/4885 |
| US-20050036946-A1 | Radio-opaque compounds, compositions containing same and methods of their synthesis and use | PLOD3, IK, SON | TTR 651/4885TP53 399/4885SLC6A4 3405/4885 |
| US-11957755-B2 | Radiopaque polymers | RXFP3, RXFP1, DAGLA | TTR 4649/4885TP53 878/4885SLC6A4 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.