SCHEMBL22897927

SCHEMBL22897927

O=[N+]([O-])c1ccc(-c2cn(-c3ccc(OC(F)(F)F)cc3)nn2)cc1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.54
CA2 P00918 4/20 0.54
CA12 O43570 1/20 0.54
CA9 Q16790 1/20 0.54
S1PR1 P21453 1/20 0.50
S1PR3 Q99500 1/20 0.50
PSD A5PKW4 1/20 0.49
KEAP1 Q14145 6/20 0.49
NFE2L2 Q16236 6/20 0.49
PTGS2 P35354 6/20 0.48
PTGS1 P23219 2/20 0.48
CA5A P35218 3/20 0.47
CA5B Q9Y2D0 3/20 0.47
PGR P06401 1/20 0.44
P2RY14 Q15391 1/20 0.44
RXRA P19793 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2B Q13224 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18031102 0.81 CA1 (0.56) CA1CA2CA12CA9S1PR1
SCHEMBL22897782 0.81 CA1 (0.56) CA1CA2CA12CA9S1PR1
SCHEMBL23557702 0.81 CA1 (0.56) CA1CA2CA12CA9S1PR1
SCHEMBL28338995 0.80 MIF (0.56) CA1CA2CA12CA9KEAP1
SCHEMBL29158482 0.80 PTGS2 (0.65) CA1CA2CA12CA9KEAP1
SCHEMBL28964572 0.80 MIF (0.56) CA1CA2CA12CA9KEAP1
SCHEMBL21814340 0.79 KEAP1 (0.73) CA1CA2CA12CA9KEAP1
SCHEMBL23557745 0.79 STS (0.67) CA1CA2CA12CA9S1PR1
SCHEMBL1260911 0.79 TLR2 (0.51) CA1CA2CA12CA9PSD
SCHEMBL1242136 0.77 PGR (0.52) CA1CA2CA12CA9PSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114072000-A Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2022-02-18 CN disclosed
WO-2021011722-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-01-21 WO disclosed