Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.58 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 3/20 | 0.45 |
| ▸ | FNTB | P49356 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663044 | 0.95 | GABBR2 (0.56) | GABBR2GABBR1MAPTPOLBCYSLTR2 | |
| SCHEMBL4403980 | 0.93 | GABBR2 (0.54) | GABBR2GABBR1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL27688433 | 0.93 | GABBR2 (0.54) | GABBR2GABBR1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL3242852 | 0.93 | GABBR2 (0.54) | GABBR2GABBR1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL2292396 | 0.89 | GABBR2 (0.61) | GABBR2GABBR1MAPTPOLBFNTA | |
| SCHEMBL28346014 | 0.89 | GABBR2 (0.61) | GABBR2GABBR1MAPTPOLBFNTA | |
| SCHEMBL14359785 | 0.89 | GABBR2 (0.66) | GABBR2GABBR1MAPTFNTAFNTB | |
| SCHEMBL9678409 | 0.88 | POLB (0.49) | GABBR2GABBR1MAPTPOLBCYSLTR2 | |
| SCHEMBL28088769 | 0.86 | ALDH1A1 (0.51) | GABBR2GABBR1POLBHDAC3HDAC4 | |
| SCHEMBL604072 | 0.86 | ESR1 (0.47) | GABBR2GABBR1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240200049-A1 | COMPOSITIONS AND METHODS OF USE THEREOF FOR MAKING POLYPEPTIDES WITH MANY INSTANCES OF NONSTANDARD AMINO ACIDS | YALE UNIVERSITY | 2024-06-20 | — | — | US | disclosed |
| WO-2023168367-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| US-11649446-B2 | Compositions and methods of use thereof for making polypeptides with many instances of nonstandard amino acids | YALE UNIVERSITY (US) | 2023-05-16 | — | — | US | disclosed |
| US-20200190500-A1 | COMPOSITIONS AND METHODS OF USE THEREOF FOR MAKING POLYPEPTIDES WITH MANY INSTANCES OF NONSTANDARD AMINO ACIDS | YALE UNIVERSITY | 2020-06-18 | — | — | US | disclosed |
| CN-105935445-B | Pharmaceutical composition and preparation method thereof containing 2- (- 4- isobutyl phenenyl) propionic acid dextrogyre | 赤峰赛林泰药业有限公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-106977395-A | A kind of process for purification of brufen | 合肥拓锐生物科技有限公司 | 2017-07-25 | — | — | CN | disclosed |
| CN-106471064-A | For preparing masterbatch and the method for sea-island fibre | 巴斯夫欧洲公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-106456662-A | Compositions of pentosan polysulfate for oral administration and methods of use thereof | 奥利金制药公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105935445-A | 2-(-4-isobutylphenyl)propionic acid dextrogyre-containing pharmaceutical composition and preparation method thereof | 赤峰赛林泰药业有限公司 | 2016-09-14 | — | — | CN | disclosed |
| US-9371296-B2 | Bicyclic 1,3,4-oxadiazole derivatives as sphingosine-1-phosphate receptors' modulators | ALLERGAN, INC. (US) | 2016-06-21 | — | — | US | disclosed |
| US-20160137616-A1 | BICYCLIC 1,3,4-OXADIAZOLE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE RECEPTORS' MODULATORS | ALLERGAN, INC. | 2016-05-19 | — | — | US | disclosed |
| WO-2015108577-A1 | DIPHENYL UREA DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-07-23 | — | — | WO | disclosed |
| US-8304223-B2 | Isoforms of pig liver esterase | ENZYMICALS AG (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20110207186-A1 | Isoforms of Pig Liver Esterase | ENZYMICALS AG (DE) | 2011-08-25 | — | — | US | disclosed |
| US-7229817-B2 | Recombinant porcine liver esterases, their use and a method for the production thereof | DEGUSSA AG (DE) | 2007-06-12 | — | — | US | disclosed |
| EP-0010346-A1 | Polyolefins stabilized against light-induced degradation and a light stabilizer composition therefor | AMERICAN CYANAMID COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |
| US-4152498-A | CORROSION RESISTANCE, HIGH MELT STABILITY, AGING AND HEAT RESISTANCE | DEMIDOVA VALENTINA M (SU) | 1979-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137616-A1 | BICYCLIC 1,3,4-OXADIAZOLE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE RECEPTORS' MODULATORS | S1PR3, S1PR1, S1PR4 | GABBR2 537/4885GABBR1 495/4885MAPT 3562/4885 |
| US-20110207186-A1 | Isoforms of Pig Liver Esterase | CES1, PIGO, PIGS | GABBR2 713/4885GABBR1 1099/4885MAPT 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.