Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.54 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.51 |
| ▸ | MMP2 | P08253 | 8/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 2/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27688433 | 1.00 | GABBR2 (0.54) | GABBR2GABBR1GPR84MMP2MMP9 | |
| SCHEMBL4403980 | 1.00 | GABBR2 (0.54) | GABBR2GABBR1GPR84MMP2MMP9 | |
| SCHEMBL7663044 | 0.98 | GABBR2 (0.56) | GABBR2GABBR1GPR84MMP2MMP9 | |
| SCHEMBL2289954 | 0.93 | GABBR2 (0.58) | GABBR2GABBR1MMP2MMP9MMP12 | |
| SCHEMBL14359785 | 0.89 | GABBR2 (0.66) | GABBR2GABBR1MAPT | |
| SCHEMBL21359025 | 0.87 | ALDH1A1 (0.49) | GABBR2GABBR1MMP2MMP9CYSLTR2 | |
| SCHEMBL10825016 | 0.87 | GPR84 (0.49) | GPR84MMP9S1PR2S1PR1 | |
| SCHEMBL2292396 | 0.86 | GABBR2 (0.61) | GABBR2GABBR1MAPT | |
| SCHEMBL28346014 | 0.86 | GABBR2 (0.61) | GABBR2GABBR1MAPT | |
| SCHEMBL9328839 | 0.86 | CERT1 (0.45) | GABBR2GABBR1MMP2MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039531-A1 | THERAPEUTIC COMPOUNDS | RESOLVYX PHARMACEUTICALS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |