Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PDE8A | O60658 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.31 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664304 | 1.00 | CHRNA7 (0.38) | CHRNA7PRMT5WDR77PIK3CDPIK3CA | |
| SCHEMBL28895432 | 0.91 | CHRNA7 (0.33) | CHRNA7PRMT5WDR77PIK3CDPIK3CA | |
| SCHEMBL28851079 | 0.76 | PIK3CD (0.40) | CHRNA7PIK3CDPIK3CAPDE8ACNR2 | |
| SCHEMBL29664318 | 0.76 | TRPV3 (0.35) | CHRNA7PIK3CDPIK3CACNR2HTR1A | |
| SCHEMBL28851189 | 0.76 | TRPV3 (0.35) | CHRNA7PIK3CDPIK3CACNR2HTR1A | |
| SCHEMBL28850945 | 0.72 | LRRK2 (0.36) | CHRNA7PIK3CDPIK3CACNR2HTR1A | |
| SCHEMBL22899867 | 0.72 | HTR1A (0.36) | CHRNA7PIK3CDPIK3CACNR2HTR1A | |
| SCHEMBL30019117 | 0.72 | HTR1A (0.36) | CHRNA7PIK3CDPIK3CACNR2HTR1A | |
| SCHEMBL20972281 | 0.71 | TRPV3 (0.40) | TRPV3 | |
| SCHEMBL27370606 | 0.71 | PDE8A (0.49) | CHRNA7PIK3CDPIK3CAPDE8ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011713-A1 | IMIDAZOPYRIMIDINES AS EED INHIBITORS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-01-21 | — | — | WO | disclosed |