Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 4/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22899862 | 0.91 | CHRNA7 (0.38) | CHRNA7MAPK1TRPV3HTR1ADRD2 | |
| SCHEMBL29664304 | 0.91 | CHRNA7 (0.38) | CHRNA7MAPK1TRPV3HTR1ADRD2 | |
| SCHEMBL29664318 | 0.71 | TRPV3 (0.35) | CHRNA7TRPV3HTR1ADRD2DRD4 | |
| SCHEMBL28851189 | 0.71 | TRPV3 (0.35) | CHRNA7TRPV3HTR1ADRD2DRD4 | |
| SCHEMBL28851079 | 0.68 | PIK3CD (0.40) | CHRNA7PIK3CDPIK3CA | |
| SCHEMBL30019117 | 0.65 | HTR1A (0.36) | CHRNA7HTR1ADRD2DRD4PIK3CD | |
| SCHEMBL22899867 | 0.65 | HTR1A (0.36) | CHRNA7HTR1ADRD2DRD4PIK3CD | |
| SCHEMBL28850945 | 0.65 | LRRK2 (0.36) | CHRNA7MAPK1HTR1ADRD2DRD4 | |
| SCHEMBL30718842 | 0.65 | AOC3 (0.34) | CHRNA7MAPK1PIK3CDPIK3CA | |
| SCHEMBL27143849 | 0.65 | AOC3 (0.34) | CHRNA7MAPK1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115212311-A | Pharmaceutical composition and application thereof | 苏州亚盛药业有限公司 | 2022-10-21 | — | — | CN | disclosed |