Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM10 | O14672 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 10/20 | 0.37 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23838548 | 0.86 | SIRT1 (0.37) | SIRT2SIRT1SIRT3 | |
| SCHEMBL14887424 | 0.78 | SIRT2 (0.42) | SIRT2SIRT1SMN1; SMN2SIRT3SIRT5 | |
| SCHEMBL17236057 | 0.78 | SIRT2 (0.42) | SIRT2SIRT1SMN1; SMN2SIRT3SIRT5 | |
| SCHEMBL16143151 | 0.78 | SIRT2 (0.42) | SIRT2SIRT1SMN1; SMN2SIRT3SIRT5 | |
| SCHEMBL24539700 | 0.77 | C3AR1 (0.42) | ADAM10MMP2MMP9MMP12MMP14 | |
| SCHEMBL22901422 | 0.77 | ITGB1 (0.37) | NPC1RAB9A | |
| SCHEMBL24701258 | 0.77 | C3AR1 (0.42) | ADAM10MMP2MMP9MMP12MMP14 | |
| SCHEMBL16644125 | 0.76 | SIRT5 (0.33) | MMP2SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL23347054 | 0.76 | SIRT2 (0.45) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL19387331 | 0.76 | SIRT2 (0.42) | SIRT2SIRT1SMN1; SMN2SIRT3SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210017274-A1 | Drug-Conjugates With a Targeting Molecule and Two Different Drugs | SORRENTO THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210017274-A1 | Drug-Conjugates With a Targeting Molecule and Two Different Drugs | ERBB2, ABCG2, DYNLL2 | ADAM10 1685/4885MMP2 3070/4885MMP9 4036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.