Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21078167 | 0.71 | TAS1R3 (0.49) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2PLK1 | |
| SCHEMBL23965631 | 0.71 | ALDH1A1 (0.47) | TAS1R3TAS1R1ALDH1A1NQO2SMN1; SMN2 | |
| SCHEMBL10308978 | 0.69 | ALDH1A1 (0.54) | TAS1R3TAS1R1ALDH1A1NQO2SMN1; SMN2 | |
| SCHEMBL25709673 | 0.69 | ALDH1A1 (0.45) | TAS1R3TAS1R1ALDH1A1NQO2SMN1; SMN2 | |
| SCHEMBL20662852 | 0.68 | TAS1R3 (0.66) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL6485939 | 0.67 | ALDH1A1 (0.56) | TAS1R3TAS1R1ALDH1A1NQO2SMN1; SMN2 | |
| SCHEMBL2514070 | 0.65 | ALDH1A1 (0.58) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL1696572 | 0.64 | PRSS1 (0.64) | ALDH1A1NQO2SMN1; SMN2IDO1PRSS1 | |
| SCHEMBL13944771 | 0.64 | ALDH1A1 (0.52) | TAS1R3TAS1R1ALDH1A1NQO2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11567719 | 0.62 | PRSS1 (0.61) | ALDH1A1NQO2SMN1; SMN2IDO1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007654-A1 | OLIGONUCLEOTIDE THERAPY FOR STARGARDT DISEASE | DEEP GENOMICS INCORPORATED (CA) | 2021-01-21 | — | — | WO | disclosed |