Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | CNR2 | P34972 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674546 | 0.85 | POLB (0.67) | POLBCNR2MEN1KMT2ACYP1A2 | |
| SCHEMBL9783328 | 0.85 | POLB (0.67) | POLBCNR2MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL27634849 | 0.83 | POLB (0.65) | POLBCNR2MEN1KMT2ACYP1A2 | |
| SCHEMBL21341573 | 0.82 | HDAC2 (0.58) | CNR2ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL19099236 | 0.81 | POLB (0.63) | POLBCNR2MEN1KMT2ACYP1A2 | |
| SCHEMBL2177216 | 0.81 | POLB (0.63) | POLBCNR2MEN1KMT2ACYP1A2 | |
| SCHEMBL2177223 | 0.81 | POLB (0.63) | POLBCNR2MEN1KMT2ACYP1A2 | |
| SCHEMBL14701618 | 0.81 | POLB (0.63) | POLBCNR2MEN1KMT2ACYP1A2 | |
| SCHEMBL8035990 | 0.81 | POLB (0.63) | POLBCNR2MEN1KMT2ACYP1A2 | |
| SCHEMBL10872603 | 0.81 | POLB (0.63) | POLBCNR2MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220125787-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO, INC. | 2022-04-28 | — | — | US | disclosed |
| US-11033635-B2 | Antibody-STING agonist conjugates and their use in immunotherapy | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| US-20210015941-A1 | ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11033635-B2 | Antibody-STING agonist conjugates and their use in immunotherapy | STING1, CGAS, MAVS | POLB 1958/4885CNR2 1986/4885MEN1 1216/4885 |
| US-20220125787-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | APLNR, AGTR1, AGTR2 | POLB 3379/4885CNR2 837/4885MEN1 3889/4885 |
| US-20210015941-A1 | ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY | STING1, CGAS, MAVS | POLB 1958/4885CNR2 1986/4885MEN1 1216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.