Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL27968557 | 0.85 | KMT2A (0.49) | KDM4EKMT2AMEN1RAB9AACHE | |
| Nitric Acid SCHEMBL3961222 | 0.85 | KMT2A (0.49) | KDM4EKMT2AMEN1RAB9AACHE | |
| SCHEMBL9696995 | 0.77 | ALDH1A1 (0.40) | KDM4ERAB9AACHEALDH1A1MAPT | |
| Nitric Acid SCHEMBL29563050 | 0.77 | ACHE (0.55) | KDM4ERAB9AACHEMAPTNPC1 | |
| SCHEMBL29562542 | 0.74 | ACHE (0.59) | KDM4ERAB9AACHEMAPTNPC1 | |
| SCHEMBL29240 | 0.74 | ACHE (0.59) | KDM4ERAB9AACHEMAPTNPC1 | |
| SCHEMBL291182 | 0.74 | ALDH1A1 (0.60) | KDM4EKMT2ARAB9AACHEALDH1A1 | |
| SCHEMBL29376451 | 0.74 | ALDH1A1 (0.60) | KDM4EKMT2ARAB9AACHEALDH1A1 | |
| Nitric Acid SCHEMBL3888885 | 0.72 | KMT2A (0.42) | KDM4EKMT2AMEN1RAB9AACHE | |
| Nitric Acid SCHEMBL9696991 | 0.72 | KDM4E (0.48) | KDM4EKMT2AMEN1RAB9AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201512-A1 | Biomarkers Indicative of Colon Cancer and Metastasis and Diagnosis and Screening Therapeutics Using the Same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2011-08-18 | — | — | US | disclosed |