Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291182 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDGLAKDM4EGAA | |
| Hydrochloric Acid SCHEMBL28881738 | 0.98 | ALDH1A1 (0.58) | ALDH1A1HPGDGLAKDM4EGAA | |
| SCHEMBL5854489 | 0.93 | ALDH1A1 (0.53) | ALDH1A1HPGDGLAKDM4EGAA | |
| SCHEMBL27873813 | 0.88 | ALDH1A1 (0.49) | ALDH1A1HPGDGLAKDM4EGAA | |
| Nitric Acid SCHEMBL3961222 | 0.87 | KMT2A (0.49) | ALDH1A1HPGDGLAKDM4EGAA | |
| Nitric Acid SCHEMBL27968557 | 0.87 | KMT2A (0.49) | ALDH1A1HPGDGLAKDM4EGAA | |
| SCHEMBL28229302 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HPGDGLAKDM4EGAA | |
| SCHEMBL38662128 | 0.84 | TSHR (0.47) | ALDH1A1HPGDGLAKDM4EGAA | |
| SCHEMBL28146547 | 0.84 | ALDH1A1 (0.45) | ALDH1A1HPGDGLAKDM4EGAA | |
| Trifluoromethanesulfonic Acid SCHEMBL3855068 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HPGDGLAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3962410-A1 | HIGH REFRACTIVE INDEX, HIGH ABBE COMPOSITIONS | Johnson & Johnson Surgical Vision, Inc. (US) | 2022-03-09 | — | — | EP | claimed |
| EP-3947633-A1 | METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES | Antheia, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |