Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | ACHE | P22303 | 11/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16741961 | 0.81 | CHRM2 (0.92) | KDM4ECYP1A2CHRM2MEN1ALDH1A1 | |
| SCHEMBL29263618 | 0.80 | HSD17B10 (0.77) | KDM4ECYP1A2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL24143750 | 0.80 | KDM4E (0.54) | KDM4ECYP1A2CYP3A4CYP2C9ACHE | |
| SCHEMBL30373907 | 0.80 | KDM4E (0.54) | KDM4ECYP1A2CYP3A4CYP2C9ACHE | |
| SCHEMBL4651676 | 0.80 | HSD17B10 (0.82) | KDM4ECYP1A2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL7946668 | 0.78 | ACHE (0.74) | ACHE | |
| SCHEMBL9827604 | 0.77 | ACHE (0.69) | ACHE | |
| SCHEMBL9777421 | 0.77 | CHRM2 (0.93) | KDM4ECYP1A2CHRM2MEN1ALDH1A1 | |
| SCHEMBL6231722 | 0.77 | CHRM2 (0.85) | KDM4ECYP1A2CHRM2MEN1ALDH1A1 | |
| SCHEMBL3281437 | 0.76 | HSD17B10 (1.00) | KDM4ECYP1A2CYP3A4CYP2C9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271961-A1 | Pan-Tropic Entry Inhibitors | UNIV EMORY (US) | 2023-08-31 | — | — | US | disclosed |
| US-20230271961-A1 | Pan-Tropic Entry Inhibitors | UNIV EMORY (US) | 2023-08-31 | — | — | US | disclosed |
| US-11649235-B2 | Pan-tropic entry inhibitors | EMORY UNIVERSITY (US) | 2023-05-16 | — | — | US | disclosed |
| US-11649235-B2 | Pan-tropic entry inhibitors | EMORY UNIVERSITY (US) | 2023-05-16 | — | — | US | disclosed |
| US-20210017178-A1 | Pan-Tropic Entry nhibitors | UNIV EMORY (US) | 2021-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649235-B2 | Pan-tropic entry inhibitors | CXCR4, CCR5, CXCL12 | KDM4E 4585/4885CYP1A2 4527/4885CYP3A4 3783/4885 |
| US-20210017178-A1 | Pan-Tropic Entry nhibitors | CXCR4, CXCL12, CCR5 | KDM4E 4254/4885CYP1A2 4559/4885CYP3A4 4089/4885 |
| US-20230271961-A1 | Pan-Tropic Entry Inhibitors | CXCR4, CCR5, CXCL12 | KDM4E 4477/4885CYP1A2 4638/4885CYP3A4 4170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.