Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22906346 | 0.88 | ACHE (0.41) | ACHEMMP13KMT2AALDH1A1BCHE | |
| SCHEMBL22904556 | 0.79 | TDP2 (0.39) | MMP13KMT2AALDH1A1TP53HTT | |
| SCHEMBL22906351 | 0.79 | ACHE (0.42) | ACHEALDH1A1BCHEOPRM1 | |
| SCHEMBL22904367 | 0.76 | BRD4 (0.45) | MMP13TP53 | |
| SCHEMBL22904366 | 0.70 | TDP2 (0.45) | ACHE | |
| SCHEMBL22904101 | 0.69 | DRD2 (0.42) | — | |
| SCHEMBL22904098 | 0.68 | DRD2 (0.41) | — | |
| SCHEMBL22904537 | 0.67 | TDP2 (0.48) | KMT2AALDH1A1TP53LMNAHTT | |
| SCHEMBL22904525 | 0.65 | TDP2 (0.54) | KMT2ALMNAHTT | |
| SCHEMBL22904127 | 0.65 | TDP2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011868-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |