Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22904367 | 0.87 | BRD4 (0.45) | TDP2MMP13TP53 | |
| SCHEMBL22904366 | 0.81 | TDP2 (0.45) | TDP2 | |
| SCHEMBL22904568 | 0.81 | MMP13 (0.39) | MMP13FFAR1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL22906345 | 0.79 | ACHE (0.41) | MMP13ALDH1A1HTTKMT2ATP53 | |
| SCHEMBL22904101 | 0.78 | DRD2 (0.42) | MTNR1AMTNR1B | |
| SCHEMBL22904537 | 0.77 | TDP2 (0.48) | TDP2ALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL22904461 | 0.76 | TDP2 (0.40) | TDP2 | |
| SCHEMBL22904525 | 0.75 | TDP2 (0.54) | TDP2HTTKMT2A | |
| SCHEMBL22904127 | 0.75 | TDP2 (0.48) | TDP2 | |
| SCHEMBL26473511 | 0.74 | TDP2 (0.45) | TDP2ALDH1A1HTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011631-A1 | FUSED-GLUTARIMIDE CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |