Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23964790 | 0.71 | SIGMAR1 (0.49) | MEN1KMT2A | |
| SCHEMBL22219455 | 0.71 | SIGMAR1 (0.33) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18476216 | 0.69 | KDM1A (0.35) | ALDH1A1 | |
| SCHEMBL24292545 | 0.69 | ESR1 (0.30) | — | |
| SCHEMBL23713679 | 0.62 | HSP90AA1 (0.38) | — | |
| SCHEMBL12964083 | 0.62 | LMNA (0.40) | HTT | |
| SCHEMBL20355351 | 0.62 | — | — | |
| SCHEMBL22791405 | 0.62 | SIGMAR1 (0.32) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22791510 | 0.61 | MEN1 (0.37) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5616902 | 0.59 | ACHE (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011913-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |