Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 5/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23964790 | 0.65 | SIGMAR1 (0.49) | — | |
| SCHEMBL24929821 | 0.65 | HSP90AA1 (0.31) | HSP90AA1KDM4ERXFP1 | |
| SCHEMBL9286815 | 0.64 | HSP90AA1 (0.47) | HSP90AA1DHFR | |
| SCHEMBL9607552 | 0.63 | DHFR (0.51) | HSP90AA1DHFR | |
| SCHEMBL22907397 | 0.62 | MEN1 (0.31) | — | |
| SCHEMBL3655582 | 0.62 | — | — | |
| SCHEMBL23094501 | 0.61 | LMNA (0.50) | KDM4ENUDT1 | |
| Hydrochloric Acid SCHEMBL28160879 | 0.61 | DHFR (0.50) | HSP90AA1DHFR | |
| SCHEMBL14757636 | 0.61 | NNMT (0.46) | HSP90AA1KDM4ERXFP1 | |
| SCHEMBL558033 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858835-A1 | PYRIMIDINE-BASED ANTIPROLIFERATIVE AGENTS | G1 Therapeutics, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |