Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229843 | 0.88 | ALDH1A1 (0.70) | ALDH1A1MAPTLMNANPSR1HSP90AA1 | |
| SCHEMBL727061 | 0.83 | TSHR (0.53) | ALDH1A1MAPTLMNANPSR1CYP2C19 | |
| SCHEMBL2163743 | 0.82 | PDPK1 (0.49) | ALDH1A1MAPTLMNANPSR1HSP90AA1 | |
| SCHEMBL3678664 | 0.78 | ALDH1A1 (0.80) | ALDH1A1MAPTLMNANPSR1HSP90AA1 | |
| SCHEMBL10917842 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNANPSR1HSP90AA1 | |
| SCHEMBL728401 | 0.76 | NPC1 (0.56) | ALDH1A1MAPTCYP2C19CYP2C9POLB | |
| SCHEMBL728174 | 0.76 | MAPT (0.71) | ALDH1A1MAPTLMNANPSR1HSP90AA1 | |
| SCHEMBL10897841 | 0.75 | KMO (0.45) | ALDH1A1MAPTLMNANPSR1CYP2C19 | |
| SCHEMBL19642630 | 0.75 | GSK3B (0.61) | ALDH1A1MAPTLMNANPSR1HSP90AA1 | |
| SCHEMBL9659013 | 0.74 | TDP1 (0.47) | ALDH1A1CYP2C19CYP2C9POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329149-B2 | Topical lightening composition and uses thereof | AVON PRODUCTS, INC. (US) | 2012-12-11 | — | — | US | claimed |
| US-20120003168-A1 | Topical Lightening Composition and Uses Thereof | AVON PRODUCTS, INC. (US) | 2012-01-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120003168-A1 | Topical Lightening Composition and Uses Thereof | TYR, AOC3, TH | ALDH1A1 129/4885MAPT 793/4885LMNA 4337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.