Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290883 | 1.00 | HIF1A (0.66) | HIF1ASLC29A1 | |
| SCHEMBL5849139 | 0.93 | SLC29A1 (0.69) | HIF1ASLC29A1 | |
| SCHEMBL5849132 | 0.93 | SLC29A1 (0.69) | HIF1ASLC29A1 | |
| SCHEMBL2288246 | 0.92 | HIF1A (0.68) | HIF1ASLC29A1 | |
| SCHEMBL2288240 | 0.92 | HIF1A (0.68) | HIF1ASLC29A1 | |
| SCHEMBL23648131 | 0.92 | SLC29A1 (0.65) | HIF1ASLC29A1 | |
| SCHEMBL8180887 | 0.90 | SLC29A1 (0.63) | HIF1ASLC29A1 | |
| SCHEMBL8180881 | 0.90 | SLC29A1 (0.63) | HIF1ASLC29A1 | |
| SCHEMBL8826179 | 0.89 | SLC29A1 (0.56) | HIF1ASLC29A1 | |
| SCHEMBL1044837 | 0.88 | HIF1A (0.61) | HIF1ASLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008007-B2 | S-adenosyl-L-methionine analogs with extended activated groups for transfer by methyltransferases | RWTH AACHEN (DE) | 2011-08-30 | — | — | US | disclosed |
| EP-1874790-B1 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2010-08-18 | — | — | EP | disclosed |
| US-20090018101-A1 | S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2009-01-15 | — | — | US | disclosed |
| EP-1874790-A2 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH Aachen (DE) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006108678-A2 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2006-10-19 | — | — | WO | disclosed |
| EP-1712557-A1 | New s-adenosyl-L-methionine analogues with extended activated groups for transfer by methyltransferases | RWTH Aachen (DE) | 2006-10-18 | — | — | EP | disclosed |
| EP-0929218-A4 | P2Y RECEPTOR ANTAGONISTS | UNIV NORTH CAROLINA (US) | 2001-05-16 | — | — | EP | disclosed |
| EP-0929218-A2 | P2Y RECEPTOR ANTAGONISTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998018430-A2 | P2Y RECEPTOR ANTAGONISTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018101-A1 | S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | BHMT2, MSRB3, PRMT3 | HIF1A 3787/4885SLC29A1 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.