SCHEMBL1044837

SCHEMBL1044837

C=C(C)CCNc1ncnc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.61
SLC29A1 Q99808 2/20 0.59
ADORA3 P0DMS8 1/20 0.52
ADORA1 P30542 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2290883 0.88 HIF1A (0.66) HIF1ASLC29A1
SCHEMBL2290876 0.88 HIF1A (0.66) HIF1ASLC29A1
SCHEMBL23648131 0.88 SLC29A1 (0.65) HIF1ASLC29A1
SCHEMBL1042589 0.87 POLB (0.54) SLC29A1
SCHEMBL8180881 0.86 SLC29A1 (0.63) HIF1ASLC29A1
SCHEMBL8180887 0.86 SLC29A1 (0.63) HIF1ASLC29A1
SCHEMBL2288246 0.86 HIF1A (0.68) HIF1ASLC29A1ADORA3
SCHEMBL2288240 0.86 HIF1A (0.68) HIF1ASLC29A1ADORA3
SCHEMBL5849139 0.85 SLC29A1 (0.69) HIF1ASLC29A1ADORA3ADORA1
SCHEMBL5849132 0.85 SLC29A1 (0.69) HIF1ASLC29A1ADORA3ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110300170-A1 HCV VACCINES INTERCELL AG (AT) 2011-12-08 US claimed
US-20110236414-A1 Bacterial Polysaccharide-Polypeptide Conjugate Compositions INTERCELL AG (AT) 2011-09-29 US claimed
EP-2345420-A1 Use of a TH1 immune response inducing adjuvant for enhancing immune responses Intercell AG (AT) 2011-07-20 EP claimed
EP-2313116-A1 IMPROVED BACTERIAL POLYSACCHARIDE-POLYPEPTIDE CONJUGATE COMPOSITIONS Intercell AG (AT) 2011-04-27 EP claimed
JP-4676426-B2 2011-04-27 JP claimed
EP-2275131-A2 HCV Vaccines Intercell AG (AT) 2011-01-19 EP claimed
US-7858588-B2 Immunostimulatory oligodeoxynucleic molecules INTERCELL AG (AT) 2010-12-28 US claimed
EP-1648502-B1 HCV VACCINES INTERCELL AG (AT) 2010-12-01 EP claimed
US-20100297170-A1 VACCINES VALNEVA AUSTRIA GMBH (AT) 2010-11-25 US claimed
WO-2010015701-A1 IMPROVED BACTERIAL POLYSACCHARIDE-POLYPEPTIDE CONJUGATE COMPOSITIONS INTERCELL AG (AT) 2010-02-11 WO claimed
US-20040248831-A1 Immunostimulatory oligodeoxynucleic molecules INTERCELL AG (AT) 2004-12-09 US claimed
WO-2004084938-A1 IMPROVED VACCINES INTERCELL AG (AT) 2004-10-07 WO claimed
EP-1450821-A1 IMMUNOSTIMULATORY OLIGODEOXYNUCLEOTIDES Intercell AG (AT) 2004-09-01 EP claimed
EP-1390495-A2 IMMUNOSTIMULATORY OLIGODEOXYNUCLEIC MOLECULES Intercell AG (AT) 2004-02-25 EP claimed
EP-1296713-B1 IMMUNOSTIMULATORY OLIGODEOXYNUCLEOTIDES INTERCELL BIOMEDIZINISCHE FORSCHUNGS & ENTWICKLUNGS GMBH (AT) 2003-09-17 EP claimed
US-20030171321-A1 Immunostimulatory oligodeoxynucleotides VALNEVA AUSTRIA GMBH (AT) 2003-09-11 US claimed
WO-2003047602-A1 IMMUNOSTIMULATORY OLIGODEOXYNUCLEOTIDES INTERCELL AG (AT) 2003-06-12 WO claimed
EP-1296713-A1 IMMUNOSTIMULATORY OLIGODEOXYNUCLEOTIDES Cistem Biotechnologies GmbH (AT) 2003-04-02 EP claimed
WO-2002095027-A2 IMMUNOSTIMULATORY OLIGODEOXYNUCLEIC MOLECULES INTERCELL AG (AT) 2002-11-28 WO claimed
WO-2001093905-A1 IMMUNOSTIMULATORY OLIGODEOXYNUCLEOTIDES INTERCELL BIOMEDIZINISCHE FORSCHUNGS- UND ENTWICKLUNGS AG (AT) 2001-12-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110300170-A1 HCV VACCINES HAVCR2, CXCR3, CD81 HIF1A 1683/4885SLC29A1 3965/4885ADORA3 4418/4885
US-20100297170-A1 VACCINES DDX1, DHX15, DDX5 HIF1A 2222/4885SLC29A1 254/4885ADORA3 763/4885
US-20040248831-A1 Immunostimulatory oligodeoxynucleic molecules NT5C3B, UMPS, NT5C2 HIF1A 3665/4885SLC29A1 75/4885ADORA3 163/4885
US-20110236414-A1 Bacterial Polysaccharide-Polypeptide Conjugate Compositions DDOST, NGLY1, DAD1 HIF1A 3242/4885SLC29A1 686/4885ADORA3 537/4885
US-20030171321-A1 Immunostimulatory oligodeoxynucleotides NT5C3B, PNP, UMPS HIF1A 3698/4885SLC29A1 113/4885ADORA3 235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.