Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22909163 | 0.87 | TSHR (0.49) | TSHRATMNPC1RAB9ALMNA | |
| SCHEMBL29671325 | 0.87 | TSHR (0.49) | TSHRATMNPC1RAB9ALMNA | |
| SCHEMBL22909474 | 0.68 | SIRT2 (0.40) | KDM4EMAPTMEN1KMT2A | |
| SCHEMBL22909401 | 0.67 | — | — | |
| SCHEMBL29671321 | 0.67 | NPC1 (0.47) | NPC1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22909154 | 0.67 | NPC1 (0.47) | NPC1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28762110 | 0.66 | MAPK10 (0.56) | TSHRATMNPC1RAB9ALMNA | |
| SCHEMBL2296586 | 0.65 | MEN1 (0.57) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL22909462 | 0.64 | L3MBTL1 (0.46) | ALDH1A1SMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL29729069 | 0.64 | L3MBTL1 (0.46) | ALDH1A1SMN1; SMN2TP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |