Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29729069 | 1.00 | L3MBTL1 (0.46) | L3MBTL1KMT2AMEN1ALDH1A1RAD52 | |
| SCHEMBL29671325 | 0.75 | TSHR (0.49) | KMT2AMEN1ALDH1A1NSD2SMN1; SMN2 | |
| SCHEMBL22909163 | 0.75 | TSHR (0.49) | KMT2AMEN1ALDH1A1NSD2SMN1; SMN2 | |
| SCHEMBL22909484 | 0.73 | CA1 (0.40) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28762068 | 0.71 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1TDP2NSD2SMN1; SMN2 | |
| SCHEMBL6086962 | 0.71 | KMT2A (0.65) | KMT2AMEN1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL22909474 | 0.68 | SIRT2 (0.40) | KMT2AMEN1TYK2 | |
| SCHEMBL22909454 | 0.68 | LMNA (0.41) | KMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL29671277 | 0.68 | CA1 (0.35) | — | |
| SCHEMBL22909293 | 0.68 | CA1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |