Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 8/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22909484 | 0.81 | CA1 (0.40) | SIRT2MEN1KMT2AKDM4E | |
| SCHEMBL22909163 | 0.77 | TSHR (0.49) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL29671325 | 0.77 | TSHR (0.49) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL29671275 | 0.74 | CA2 (0.48) | KDM4E | |
| SCHEMBL568681 | 0.73 | TSHR (0.53) | SIRT2IDH1MEN1KMT2ACCR6 | |
| SCHEMBL22909462 | 0.68 | L3MBTL1 (0.46) | MEN1KMT2ATYK2 | |
| SCHEMBL29729069 | 0.68 | L3MBTL1 (0.46) | MEN1KMT2ATYK2 | |
| SCHEMBL22909113 | 0.68 | TSHR (0.42) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL12017952 | 0.67 | SLC22A12 (0.48) | MEN1KMT2AKDM4ECCR6SLC22A12 | |
| SCHEMBL22909451 | 0.67 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |