Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22909600 | 0.87 | IDO1 (0.36) | CA12CA1CA2CA7CA13 | |
| SCHEMBL17629199 | 0.82 | CA12 (0.66) | CA12CA1CA2CA7CA13 | |
| SCHEMBL22909469 | 0.77 | ALDH1A1 (0.37) | CA12CA1CA2CA7CA13 | |
| SCHEMBL22909374 | 0.75 | TAAR1 (0.39) | CA12CA1CA2CA7CA13 | |
| SCHEMBL13778721 | 0.75 | CA12 (0.58) | CA12CA1CA2CA7CA13 | |
| SCHEMBL22909165 | 0.74 | CA12 (0.61) | CA12CA1CA2CA7CA13 | |
| SCHEMBL22909382 | 0.73 | SIGMAR1 (0.40) | CA12CA1CA2CA7CA13 | |
| SCHEMBL31034705 | 0.73 | CA12 (0.65) | CA12CA1CA2CA7CA13 | |
| SCHEMBL31034586 | 0.72 | CA12 (0.55) | CA12CA1CA2CA7CA13 | |
| SCHEMBL24628141 | 0.72 | MAOA (0.53) | POLBMETAP2HSD17B10ALDH1A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |