Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091158 | 0.84 | MGAM (0.53) | ADRA2AADRA1AGAACYP3A4TSHR | |
| SCHEMBL31588099 | 0.84 | MGAM (0.53) | ADRA2AADRA1AGAACYP3A4TSHR | |
| SCHEMBL22910136 | 0.81 | CA12 (0.54) | ADRA2AADRA1AGAAPOLBGFER | |
| SCHEMBL1922536 | 0.78 | ACHE (0.48) | ADRA2AADRA1APOLBCYP3A4TSHR | |
| SCHEMBL17409054 | 0.77 | PDE2A (0.39) | — | |
| SCHEMBL17409058 | 0.77 | PDE2A (0.39) | — | |
| SCHEMBL20970925 | 0.76 | ADRA2A (0.57) | ADRA2AADRA1AGAAPOLBGFER | |
| SCHEMBL29543324 | 0.76 | ADRA2A (0.57) | ADRA2AADRA1AGAAPOLBGFER | |
| SCHEMBL9173075 | 0.74 | ADRA2A (0.56) | ADRA2AADRA1AADRB2ADRB1ADRB3 | |
| SCHEMBL29825075 | 0.74 | ADRA1A (0.75) | ADRA2AADRA1ATSHRADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3389379-B1 | MICROBIOCIDAL PHENYLAMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-20 | — | — | EP | disclosed |