SCHEMBL7091158

SCHEMBL7091158

CCC(O)c1cc(OC)c(OC)cc1OC

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.53
GAA P10253 1/20 0.53
SI P14410 1/20 0.53
MGAM2 Q2M2H8 1/20 0.53
ADRA2A P08913 1/20 0.44
ADRA1A P35348 1/20 0.44
TOP1 P11387 4/20 0.42
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
PPARG P37231 1/20 0.41
PPARD Q03181 1/20 0.41
PPARA Q07869 1/20 0.41
NFKB1 P19838 1/20 0.40
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31588099 1.00 MGAM (0.53) MGAMGAASIMGAM2ADRA2A
SCHEMBL22910035 0.84 ADRA2A (0.42) MGAMGAASIMGAM2ADRA2A
SCHEMBL5304171 0.78 TAAR1 (0.64) CYP3A4TSHRNFKB1
SCHEMBL5474209 0.78 TAAR1 (0.64) CYP3A4TSHRNFKB1
SCHEMBL18287898 0.78 MGAM (0.61) MGAMGAASIMGAM2ADRA2A
SCHEMBL9173075 0.77 ADRA2A (0.56) ADRA2AADRA1AADRB2ADRB1ADRB3
SCHEMBL10086096 0.77 ADRA1A (0.75) ADRA2AADRA1ATSHRADRB2ADRB1
SCHEMBL1922536 0.77 ACHE (0.48) ADRA2AADRA1ACYP3A4TSHRNFKB1
SCHEMBL29825075 0.77 ADRA1A (0.75) ADRA2AADRA1ATSHRADRB2ADRB1
SCHEMBL23322870 0.76 ADRA1A (0.50) ADRA2AADRA1ACYP3A4TSHRPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108727168-A A kind of alpha-ararin synthesis technology 岳阳正昊化学科技有限公司 2018-11-02 CN claimed
US-6590127-B1 Formation of alpha-asarone, isoacoramone and 2,4,5-trimethoxycinnamaldehyde in one step process via 2,3-dichloro-5,6-dicyano-1,4-benzoquinone assisted dehydrogenation/oxidation of 2,4,5-trimethoxyphenylpropane COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2003-07-08 US claimed
CN-108727168-A A kind of alpha-ararin synthesis technology 岳阳正昊化学科技有限公司 2018-11-02 CN disclosed
CN-108727168-A A kind of alpha-ararin synthesis technology 岳阳正昊化学科技有限公司 2018-11-02 CN disclosed
CN-102199077-B Method for producing (E)-2,4,5-trimethoxy-1-propenylbenzene LU CHAO 2013-01-23 CN disclosed
CN-102199077-A Method for producing (E)-2,4,5-trimethoxy-1-propenylbenzene CHAO LU 2011-09-28 CN disclosed
WO-2003082786-A1 A PROCESS FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE ALPHA-ASARONE FROM TOXIC BETA-ASARONE RICH ACORUS CALAMUS OIL COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-09 WO disclosed
WO-2003082786-A1 A PROCESS FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE ALPHA-ASARONE FROM TOXIC BETA-ASARONE RICH ACORUS CALAMUS OIL COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-09 WO disclosed
US-6590127-B1 Formation of alpha-asarone, isoacoramone and 2,4,5-trimethoxycinnamaldehyde in one step process via 2,3-dichloro-5,6-dicyano-1,4-benzoquinone assisted dehydrogenation/oxidation of 2,4,5-trimethoxyphenylpropane COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2003-07-08 US disclosed
US-6590127-B1 Formation of alpha-asarone, isoacoramone and 2,4,5-trimethoxycinnamaldehyde in one step process via 2,3-dichloro-5,6-dicyano-1,4-benzoquinone assisted dehydrogenation/oxidation of 2,4,5-trimethoxyphenylpropane COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2003-07-08 US disclosed