Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 3/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | ATXN2 | Q99700 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16759896 | 1.00 | CCNC (0.41) | CCNCCDK8SLC6A7LSSHPGD | |
| SCHEMBL16962830 | 0.93 | SLC6A7 (0.47) | CCNCCDK8SLC6A7LSSHPGD | |
| SCHEMBL21323113 | 0.93 | SLC6A7 (0.47) | CCNCCDK8SLC6A7LSSHPGD | |
| SCHEMBL16962831 | 0.93 | SLC6A7 (0.47) | CCNCCDK8SLC6A7LSSHPGD | |
| SCHEMBL20107136 | 0.93 | SLC6A7 (0.47) | CCNCCDK8SLC6A7LSSHPGD | |
| SCHEMBL16759821 | 0.93 | SLC6A7 (0.45) | CCNCCDK8SLC6A7HPGDHTR2B | |
| SCHEMBL22911178 | 0.90 | MGLL (0.42) | CCNCCDK8SLC6A7HPGDHTR2B | |
| SCHEMBL16759760 | 0.90 | MGLL (0.42) | CCNCCDK8SLC6A7HPGDHTR2B | |
| SCHEMBL22911067 | 0.89 | HPGD (0.45) | CCNCCDK8SLC6A7HPGDENPP2 | |
| SCHEMBL16759749 | 0.89 | HPGD (0.45) | CCNCCDK8SLC6A7HPGDENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210015792-A1 | OCTAHYDRO-CYCLOBUTA[1,2-c;3,4-c']DIPYRROL-2-YL | HOFFMANN-LA ROCHE INC. (US) | 2021-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210015792-A1 | OCTAHYDRO-CYCLOBUTA[1,2-c;3,4-c']DIPYRROL-2-YL | NPY1R, NPY2R, DECR1 | CCNC 24/4885CDK8 1582/4885SLC6A7 3934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.