Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22912292 | 0.89 | SLC6A4 (0.37) | SLC6A4SLC9A1KEAP1HPGDPOLB | |
| SCHEMBL12560105 | 0.71 | SLC9A1 (0.50) | SLC6A4SLC9A1KEAP1HPGDNOTUM | |
| SCHEMBL19805979 | 0.70 | ALDH1A1 (0.50) | POLBKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL29975783 | 0.70 | SLC9A1 (0.48) | SLC6A4SLC9A1KEAP1HPGDPOLB | |
| SCHEMBL282111 | 0.70 | SLC9A1 (0.48) | SLC6A4SLC9A1KEAP1HPGDPOLB | |
| SCHEMBL19805948 | 0.69 | — | — | |
| SCHEMBL19806035 | 0.69 | SLC9A1 (0.41) | SLC6A4SLC9A1KEAP1HPGDPOLB | |
| SCHEMBL8828592 | 0.69 | SLC9A1 (0.47) | SLC6A4SLC9A1KEAP1HPGDNOTUM | |
| SCHEMBL22912199 | 0.68 | ALDH1A1 (0.49) | KDM4EHTTALDH1A1NPC1RAB9A | |
| SCHEMBL22862868 | 0.67 | KEAP1 (0.48) | SLC6A4SLC9A1KEAP1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |