Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SDHB | P21912 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875023 | 0.92 | MAPT (0.39) | ALDH1A1MAPTTP53SDHBSMN1; SMN2 | |
| SCHEMBL28307461 | 0.85 | SDHB (0.39) | ALDH1A1TSHRLMNAMAPTTP53 | |
| SCHEMBL28306389 | 0.82 | SDHB (0.49) | ALDH1A1LMNAMAPTTP53SDHB | |
| SCHEMBL28306292 | 0.80 | SDHB (0.41) | SDHB | |
| SCHEMBL28306261 | 0.73 | SDHB (0.58) | ALDH1A1TSHRLMNAMAPTTP53 | |
| SCHEMBL19805761 | 0.73 | SDHB (0.58) | SDHB | |
| Pyridine SCHEMBL28306262 | 0.71 | EPHX2 (0.34) | ALDH1A1TSHRLMNAMAPTSDHB | |
| SCHEMBL28306340 | 0.70 | TP53 (0.37) | ALDH1A1TSHRLMNAMAPTTP53 | |
| SCHEMBL28306272 | 0.70 | ALDH1A1 (0.40) | ALDH1A1TSHRMAPTTP53SDHB | |
| SCHEMBL28307457 | 0.70 | SDHB (0.56) | ALDH1A1LMNAMAPTTP53SDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |