SCHEMBL2291236

SCHEMBL2291236

CCCCCCCCCCCCC/C=C/c1cccc(O)c1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LCK P06239 2/20 0.49
P4HB P07237 1/20 0.45
ABL1 P00519 1/20 0.45
BCR P11274 1/20 0.45
CCNB2 O95067 1/20 0.45
CDK1 P06493 1/20 0.45
CDK4 P11802 1/20 0.45
CCNB1 P14635 1/20 0.45
CCND1 P24385 1/20 0.45
CCNB3 Q8WWL7 1/20 0.45
TNNC1 P63316 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16974820 1.00 LCK (0.49) LCKP4HBABL1BCRCCNB2
SCHEMBL10742841 1.00 LCK (0.49) LCKP4HBABL1BCRCCNB2
SCHEMBL30219517 1.00 LCK (0.49) LCKP4HBABL1BCRCCNB2
SCHEMBL10753151 1.00 LCK (0.49) LCKP4HBABL1BCRCCNB2
SCHEMBL10742837 1.00 LCK (0.49) LCKP4HBABL1BCRCCNB2
SCHEMBL16974816 1.00 LCK (0.49) LCKP4HBABL1BCRCCNB2
SCHEMBL16535943 1.00 LCK (0.49) LCKP4HBABL1BCRCCNB2
SCHEMBL16679898 1.00 LCK (0.49) LCKP4HBABL1BCRCCNB2
SCHEMBL122640 1.00 LCK (0.49) LCKP4HBABL1BCRCCNB2
SCHEMBL10753147 1.00 LCK (0.49) LCKP4HBABL1BCRCCNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9849101-B2 Method for enhancing amidohydrolase activity of fatty acid amide hydrolase RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2017-12-26 US disclosed
US-20170000748-A1 METHOD FOR ENHANCING AMIDOHYDROLASE ACTIVITY OF FATTY ACID AMIDE HYDROLASE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2017-01-05 US disclosed
US-9474271-B2 Method for enhancing amidohydrolase activity of fatty acid amide hydrolase RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2016-10-25 US disclosed
US-9315676-B2 Green approach in metal nanoparticle-embedded antimicrobial coatings from vegetable oils and oil-based materials RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2016-04-19 US disclosed
US-20150359218-A1 METHOD FOR ENHANCING AMIDOHYDROLASE ACTIVITY OF FATTY ACID AMIDE HYDROLASE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK 2015-12-17 US disclosed
EP-2945483-A1 METHOD FOR ENHANCING AMIDOHYDROLASE ACTIVITY OF FATTY ACID AMIDE HYDROLASE Research Foundation Of The City University Of New York (US) 2015-11-25 EP disclosed
WO-2014113689-A1 METHOD FOR ENHANCING AMIDOHYDROLASE ACTIVITY OF FATTY ACID AMIDE HYDROLASE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2014-07-24 WO disclosed
US-20110189250-A1 GREEN APPROACH IN METAL NANOPARTICLE-EMBEDDED ANTIMICROBIAL COATINGS FROM VEGETABLE OILS AND OIL-BASED MATERIALS JOHN GEORGE 2011-08-04 US disclosed
WO-2009091900-A1 A GREEN APPROACH IN METAL NANOPARTICLE-EMBEDDED ANTIMICROBIAL COATINGS FROM VEGETABLE OILS AND OIL-BASED MATERIALS RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2009-07-23 WO disclosed
US-20090068126-A1 Composition for surface photoprotection SOARES ROMEIRO LUIZ ANTONIO 2009-03-12 US disclosed
EP-1812027-A2 COMPOUNDS CAPABLE OF ABSORBING ULTRAVIOLET RADIATION, COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION Universidade Federal Do Rio De Janeiro - UFRJ (BR) 2007-08-01 EP disclosed
WO-2006042391-A2 PHOTOPROTECTIVE PHENOL DERIVATIVES OBTAINED FROM CASHEW NUT-SHELL LIQUID UNIVERSIDADE FEDERAL DO RIO DE JANEIRO-UFRJ (BR) 2006-04-27 WO disclosed
EP-0399350-A2 Curable compositions THE DOW CHEMICAL COMPANY (US) 1990-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068126-A1 Composition for surface photoprotection S100A10, CD63, S100A9 LCK 4317/4885P4HB 1147/4885ABL1 1208/4885
US-20170000748-A1 METHOD FOR ENHANCING AMIDOHYDROLASE ACTIVITY OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, NAAA LCK 4711/4885P4HB 560/4885ABL1 4186/4885
US-20150359218-A1 METHOD FOR ENHANCING AMIDOHYDROLASE ACTIVITY OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, NAAA LCK 4554/4885P4HB 925/4885ABL1 4263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.