SCHEMBL22912581

SCHEMBL22912581

COCc1ncc(F)cc1F

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AGBL2 Q5U5Z8 1/20 0.40
KLKB1 P03952 1/20 0.38
MAPKAPK5 Q8IW41 11/20 0.35
MAPK14 Q16539 10/20 0.35
MAPK1 P28482 9/20 0.35
ADORA2A P29274 1/20 0.34
MCHR1 Q99705 3/20 0.33
GRM5 P41594 1/20 0.32
MAPKAPK2 P49137 1/20 0.31
NAAA Q02083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28002299 0.83 AGBL2 (0.38) AGBL2MAPKAPK5MAPK14MAPK1ADORA2A
SCHEMBL25124308 0.82 LMNA (0.37) AGBL2MAPKAPK5MAPK14MAPK1
SCHEMBL31539703 0.81 AGBL2 (0.38) AGBL2KLKB1ADORA2AGRM5
SCHEMBL22048116 0.81 TET2 (0.30) NAAA
SCHEMBL22912583 0.81 KLKB1 (0.41) KLKB1MAPKAPK5MAPK14MAPK1NAAA
SCHEMBL134813 0.77 AGBL2 (0.43) AGBL2MAPK1ADORA2A
SCHEMBL29941432 0.77 AGBL2 (0.43) AGBL2MAPK1ADORA2A
SCHEMBL10264384 0.77 AGBL2 (0.43) AGBL2MAPK1ADORA2A
SCHEMBL12468456 0.77 AGBL2 (0.38) AGBL2MAPKAPK5MAPK14MAPK1ADORA2A
SCHEMBL25121174 0.77 GRM5 (0.41) MAPK1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240229063-A1 TRANSGENIC CORN EVENT ZM_CSM63715 AND METHODS FOR DETECTION AND USES THEREOF MONSANTO TECHNOLOGY LLC (US) 2024-07-11 US disclosed
US-20240025862-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-01-25 US disclosed
WO-2023161172-A1 SUBSTITUTED N-BENZOIC ACID URACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2023-08-31 WO disclosed
EP-4230621-A1 SUBSTITUTED N-BENZOIC ACID URACILS, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS Bayer AG (DE) 2023-08-23 EP disclosed
EP-4230620-A1 SUBSTITUTED N-AMINO-N-BENZOIC ACID URACILS, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS Bayer Aktiengesellschaft (DE) 2023-08-23 EP disclosed
WO-2021013800-A1 SUBSTITUTED N-PHENYL-N-AMINOUARCILS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-01-28 WO disclosed
WO-2021013799-A1 SUBSTITUTED N-PHENYL URACILS, SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-01-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025862-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES PFAS, DDT, NOTUM AGBL2 1419/4885KLKB1 4881/4885MAPKAPK5 1812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.